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1.
Phys Rev Lett ; 127(24): 245001, 2021 Dec 10.
Artigo em Inglês | MEDLINE | ID: mdl-34951808

RESUMO

In inertial confinement approaches to fusion, the asymmetry of target implosion is a major obstacle to achieving high gain in the laboratory. A recently proposed octahedral spherical hohlraum makes it possible to naturally create spherical target irradiation without supplementary symmetry control. Before any decision is made to pursue an ignition-scale laser system based on the octahedral hohlraum, one needs to test the concept with the existing facilities. Here, we report a proof-of-concept experiment for the novel octahedral hohlraum geometry on the cylindrically configured SGIII laser facility without a symmetry control. All polar and equatorial self-emission images of the compressed target show a near round shape of convergence ratio 15 under both square and shaped laser pulses. The observed implosion performances agree well with the ideal spherical implosion simulation. It also shows limitations with using the existing facilities and adds further weight to the need to move to a spherical port geometry for future ignition laser facilities.

2.
Sci Rep ; 11(1): 2017, 2021 01 21.
Artigo em Inglês | MEDLINE | ID: mdl-33479397

RESUMO

The experiment of inertial confinement fusion by the "ShengGuang (SG)-III" prototype laser facility is a transient and extreme reaction process within several nanoseconds, which could form a very complicated and intense electromagnetic field around the target chamber of the facility and may lead to harmful effect on people around. In particular, the biological effects arising from such specific environment field could hardly be ignored and have never been investigated yet, and thus, we reported on the investigation of the biological effects of radiation on HaCat cells and PC12 cells to preliminarily assess the biological safety of the target range of the "SG-III" prototype laser facility. The viability revealed that the damage of cells was dose-dependent. Then we compared the transcriptomes of exposed and unexposed PC12 cells by RNA-Seq analysis based on Illumina Novaseq 6000 platform and found that most significantly differentially expressed genes with corresponding Gene Ontology terms and pathways were strongly involved in proliferation, transformation, necrosis, inflammation response, apoptosis and DNA damage. Furthermore, we find increase in the levels of several proteins responsible for cell-cycle regulation and tumor suppression, suggesting that pathways or mechanisms regarding DNA damage repair was are quickly activated. It was found that "SG-III" prototype radiation could induce DNA damage and promote apoptotic necrosis.


Assuntos
Radiação Eletromagnética , Perfilação da Expressão Gênica , Lasers/efeitos adversos , Transcriptoma/genética , Animais , Apoptose/genética , Apoptose/efeitos da radiação , Pontos de Checagem do Ciclo Celular/genética , Pontos de Checagem do Ciclo Celular/efeitos da radiação , Dano ao DNA/genética , Dano ao DNA/efeitos da radiação , Reparo do DNA/genética , Reparo do DNA/efeitos da radiação , Sequenciamento de Nucleotídeos em Larga Escala , Humanos , Células PC12 , Ratos , Transcriptoma/efeitos da radiação
3.
Rev Sci Instrum ; 91(2): 023508, 2020 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-32113434

RESUMO

A neutron time-of-flight (nTOF) system has been implemented at the largest laser facility in China. The nTOF system is used to measure neutron spectra in inertial confinement fusion experiments. The nTOF system consists of 11 fast plastic scintillation detectors. The detectors employed three designs to measure neutron yield, ion temperature, and neutron bang time. The nTOF system is capable of measuring the primary neutron yield from 107 to 1013, secondary DT neutron yield from 106 to 108, and ion temperature and neutron bang time yields from 108 to 1013. The accuracies of the nTOF system are about 10% for neutron yield and ion temperature measurements and better than 60 ps for neutron bang time measurements. The nTOF system has become one of the most important diagnostics for implosions, and it is used for more than 200 shots per year.

4.
Chem Commun (Camb) ; 46(30): 5503-5, 2010 Aug 14.
Artigo em Inglês | MEDLINE | ID: mdl-20593070

RESUMO

A luminescent metal-organic framework with small micropores for the enhanced recognition of Cu(2+) exhibits highly sensitive and selective sensing of Cu(2+) in aqueous solution.


Assuntos
Cobre/análise , Compostos Organometálicos/química , Luminescência , Porosidade , Água/química
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